How a little-known 18th century instrument maker may have inspired the first clinical trial of the modern age

Francis Hauksbee the Younger laid out a 10 -step approach to testing new treatments for scurvy in 1747 .

The design of his study likely sparked James Lind’s pivotal research that identified oranges and lemons as a cure for the scourge of sailors.

In the 18th century , for many physicians who typically formulated their own medicines, it would have been highly unusual to prescribe someone else's treatment.

There is no evidence to suggest that Hauksbee ’s study ever took place, according to the new research.

The London medical faculty had no interest in pursuing such a study from a nonphysician.

In 1747 , Lind assessed a dozen patients with scurvy aboard the Royal Navy ship HMS Salisbury .

“My inspiration for studying Hauksbee lies in a fascination with the history of medicine and a belief that medical students can learn from the clinical advances and errors made by doctors over the centuries ,” Cooper said. “This is particularly true with regard to the history of the development of drug trials. I use examples like Hauksbee ’s study proposal to help medical students understand the strengths and weaknesses of treatment trials.” For more CNN news and newsletters create an account at CNN.com .