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Researchers uncover what drives aggressive bone cancer

ScienceDaily
Summary
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79% Informative

Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 and 20 .

New research solves the mystery of what drives the genomic rearrangements causing the aggressive development and evolution of bone cancer tumours.

The study also presents a prognostic biomarker -- a biological characteristic of cancer cells that can help predict patient outcome -- that might be used to anticipate the likely course of the disease.

The finding has significant implications for the treatment of diverse cancer types.

Loss of heterozygosity ( LOH ) occurs when one copy of a genomic region is lost.

In osteosarcoma , a high degree of LOH across the genome predicts a lower survival probability.

LOH could help identify patients who are unlikely to benefit from treatment which can have very unpleasant effects.

VR Score

89

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98

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27

Article tone

formal

Language

English

Language complexity

79

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not offensive

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not hateful

Attention-grabbing headline

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Known propaganda techniques

not detected

Time-value

long-living

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