F-actin inhibits neuronal function
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aged fruit fliesMedical Xpress - medical research advances and health news
•Scientists can reverse brain aging in fruit flies by preventing buildup of a common protein
88% Informative
A common cell structural protein called filamentous actin, or F-actin , inhibits a key process that removes unnecessary or dysfunctional components within cells.
The resulting accumulation of waste diminishes neuronal functions and contributes to cognitive decline.
By tweaking a few specific genes in aging fruit flies' neurons, the researchers prevented F-actsin buildup and maintained cellular recycling.
DOI: 10.1038 /s41467-024-53389-w Provided by University of California , Los AngelesThis story was originally published on Medical Xpress . Subscribe to our newsletter for the latest sci-tech news updates..
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