Gluccarpidase Antidotes Kidney Toxicity

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chemotherapy drug methotrexate

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chemotherapy antidote

ScienceDaily

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Study finds chemotherapy antidote could improve recovery after chemotherapy-induced kidney toxicity

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Study finds chemotherapy antidote could improve recovery after chemotherapy-induced kidney toxicity.

FDA -approved medication called glucarpidase could serve as an antidote to kidney toxicity in patients receiving the chemotherapy drug methotrexate (MTX) The researchers examined the association between glucaridase treatment and outcomes of patients with MTX-induced acute kidney injury (AKI).

In addition to Gupta and Leaf, Mass General Brigham authors include Sarah A. Kaunfer , Shobana Krishnamurthy , Rafia Ali , Osman A. Yilmam , Sophia L. Wells , Jessica L. Ortega , Olivia L. Green-Lingren , Jian Ni , Meghan E. Sise .