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Understanding Metabolism, Aging and Disease

This is a news story, published by Yahoo, that relates primarily to Melanie R. McReynolds news.

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metabolic homeostasis

The Conversation

The Conversation

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What links aging and disease? A growing body of research says it’s a faulty metabolism

The Conversation

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87% Informative

A dysfunctional metabolism is linked to many hallmarks of aging cells, such as telomere shortening and genomic instability.

Disrupting homeostasis destabilizes the body’s internal environment, leading to imbalances that can trigger a cascade of health issues, including metabolic disorders, chronic diseases.

More research can improve our understanding of how metabolism affects stress responses and cellular balance throughout life. This article is republished from The Conversation , a nonprofit, independent news organization bringing you facts and trustworthy analysis to help you make sense of our complex world. It was written by: Melanie R. McReynolds , Penn State Read more: Melanie R. McReynolds receives funding from the Howard Hughes Medical Institute Hanna H. Gray Fellows Program Faculty Phase and the Burroughs Welcome Fund PDEP Transition to Faculty ..

VR Score

86

Informative language

85

Neutral language

48

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informal

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English

Language complexity

75

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not offensive

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not hateful

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not detected

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not detected

Time-value

long-living

External references

31

https://www.science.org/doi/10.1126/science.abm6131 https://doi.org/10.3390/ijms24065742 https://doi.org/10.1126/science.aac4854 http://creativecommons.org/licenses/by-sa/4.0/https://theconversation.com/cells-become-zombies-when-the-ends-of-their-chromosomes-are-damaged-a-tactic-both-helpful-and-harmful-for-health-186445 https://www.britannica.com/science/homeostasis https://doi.org/10.1016/j.neuropharm.2016.03.024 http://theconversation.com/repurposing-generic-drugs-can-reduce-time-and-cost-to-develop-new-treatments-but-low-profitability-remains-a-barrier-174874?utm_source=Yahoo&utm_medium=related-link&utm_campaign=related-link2&utm_content=article-236047 https://doi.org/10.1161/ATVBAHA.112.252759 https://theconversation.com/profiles/melanie-r-mcreynolds-1550529?utm_source=Yahoo&utm_medium=related-link&utm_campaign=byline-link&utm_content=article-236047 https://doi.org/10.1038/s41580-020-00313-x https://scholar.google.com/citations?user=QFZydSIAAAAJ&hl=en https://commons.wikimedia.org/wiki/File:IDO1_prot.png https://doi.org/10.1038/s41380-019-0414-4 https://theconversation.com/institutions/penn-state-1258?utm_source=Yahoo&utm_medium=related-link&utm_campaign=byline-link&utm_content=article-236047 https://doi.org/10.1016/j.mce.2016.11.003 https://doi.org/10.1021/acschemneuro.3c00532 https://doi.org/10.1016/j.cmet.2010.05.001 https://www.genome.gov/genetics-glossary/Mitochondria https://www.mcreynoldslab.com/https://doi.org/10.1016/j.tibs.2006.11.006 https://theconversation.com/hangry-bacteria-in-your-gut-microbiome-are-linked-to-chronic-disease-feeding-them-what-they-need-could-lead-to-happier-cells-and-a-healthier-body-199486 https://doi.org/10.1038/s41586-020-03160-0 https://doi.org/10.1038/s12276-021-00677-w https://doi.org/10.1016/j.tcb.2019.12.001 http://theconversation.com/us?utm_source=Yahoo&utm_medium=related-link&utm_campaign=related-link-0&utm_content=article-236047 http://theconversation.com/are-you-a-rapid-ager-biological-age-is-a-better-health-indicator-than-the-number-of-years-youve-lived-but-its-tricky-to-measure-198849?utm_source=Yahoo&utm_medium=related-link&utm_campaign=related-link1&utm_content=article-236047 https://theconversation.com/aging-is-complicated-a-biologist-explains-why-no-two-people-or-cells-age-the-same-way-and-what-this-means-for-anti-aging-interventions-202096 http://theconversation.com/aging-is-complicated-a-biologist-explains-why-no-two-people-or-cells-age-the-same-way-and-what-this-means-for-anti-aging-interventions-202096?utm_source=Yahoo&utm_medium=related-link&utm_campaign=related-link0&utm_content=article-236047 https://doi.org/10.1038/s41598-023-50990-9 https://theconversation.com/what-is-metabolism-a-biochemist-explains-how-different-people-convert-energy-differently-and-why-that-matters-for-your-health-211816

Source diversity

9

www.science.org doi.org creativecommons.org theconversation.com www.britannica.com scholar.google.com commons.wikimedia.org www.genome.gov www.mcreynoldslab.com

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