The “Pfizer Boob Job”: A Case of Unexplained Gigantomastia

The patient in this case report presented with both occurrences and experienced massive breast enlargement 1 week postadministration of the Pfizer /BioNTech COVID-19 vaccine.

Gigantomastia is a rare condition characterized by rapid, diffuse, and excessive breast growth.

The patient initially reported tingling paresthesia in her breasts, followed by sudden bilateral growth which worsened after receiving the second vaccine dose.

PASH-associated gigantomastia is rare, with fewer than 20 documented cases.

Here, we present the case of a healthy female patient who experienced rapid breast enlargement, progressing from a B cup to a triple G cup over 6 months , beginning 1 week following Pfizer COVID-19 vaccination.

She underwent bilateral reduction mammoplasty, complicated by intraoperative bleeding, necessitating postoperative transfusions.

At 5 months postoperation, breast asymmetry and areolar hypopigmentation were noted.

Pseudoangiomatous stromal hyperplasia (PASH) syndrome causes gigantomastia in a 33-year-old pregnant woman.

This section collects any data citations, data availability statements, or supplementary materials included in this article.

For more information on PASH syndrome, visit http://www.pcmc.org/pashistha.