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Preclinical study finds surges in estrogen promote binge drinking in females

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79% Informative

Estrogen regulates binge drinking in females, causing them to “pregame” consume large quantities of alcohol in the first 30 minutes after it’s offered.

The findings could lead to novel approaches for treating alcohol use disorder.

Estrogen is binding to receptors on the neurons’ surface, where it modulates cell-cell communication.

“Combining this drug with compounds that modulate the downstream effects of the chemicals produced by the BNST neurons could potentially provide a new, targeted approach for treating alcohol use disorder,” Dr. Pleil said. Journal Nature Communications .