Genetic Disorder Causes Aortic Aneurysms
This is a news story, published by ScienceDaily, that relates primarily to Loeys-Dietz news.
Loeys-Dietz news
For more Loeys-Dietz news, you can click here:
more Loeys-Dietz newsdisease research news
For more disease research news, you can click here:
more disease research newsScienceDaily news
For more news from ScienceDaily, you can click here:
more news from ScienceDailyAbout the Otherweb
Otherweb, Inc is a public benefit corporation, dedicated to improving the quality of news people consume. We are non-partisan, junk-free, and ad-free. We use artificial intelligence (AI) to remove junk from your news feed, and allow you to select the best health news, business news, entertainment news, and much more. If you like disease research news, you might also like this article about
Aortic Diseases. We are dedicated to bringing you the highest-quality news, junk-free and ad-free, about your favorite topics. Please come every day to read the latest other vascular connective tissue disorders news, aortic root aneurysm news, disease research news, and other high-quality news about any topic that interests you. We are working hard to create the best news aggregator on the web, and to put you in control of your news feed - whether you choose to read the latest news through our website, our news app, or our daily newsletter - all free!
aortic aneurysmsScienceDaily
•Scientists identify a probable contributor to weakness of the aorta in people with genetic disorder
81% Informative
Johns Hopkins Medicine scientists identify a probable contributor to weakness of the aorta in people with genetic disorder.
Loeys-Dietz syndrome affects the craniofacial, skeletal, cutaneous, gastrointestinal and cardiovascular systems.
Aneurysms are bulging enlargements of an artery that predispose it to life-threatening tears (dissections) or rupture.
Aortic cells expressing high levels of Gata4 were present in higher numbers in the aortic root of mice and humans with Loeys-Dietz syndrome.
Smooth muscle cells with the Tgfbr1 mutation seem to be unable to properly degrade excess protein, resulting in its accumulation.
The scientists hope to learn why the mutation that causes the mutation leads to an accumulation of the protein.
The research was funded by the National Institutes of Health .
VR Score
91
Informative language
97
Neutral language
78
Article tone
formal
Language
English
Language complexity
68
Offensive language
not offensive
Hate speech
not hateful
Attention-grabbing headline
not detected
Known propaganda techniques
not detected
Time-value
long-living
External references
no external sources
Source diversity
no sources
Affiliate links
no affiliate links