Misdiagnosis in Parkinson's Diagnosis
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synuclein testingtorontosun
•Parkinson's is often misdiagnosed. New tests may change that.
86% Informative
Nearly 42% of people are initially misdiagnosed with Parkinson’s disease, according to studies.
Diagnosis is currently based on a visual clinical exam in which a physician looks for motor symptoms such as slowed movement, tremor or rigidity.
New biomarker tests could improve diagnostic accuracy in early Parkinson's disease and diagnose it before symptoms begin.
Alpha-synuclein is a hallmark of synucleinopathies, a group of neurodegenerative diseases characterized by aggregates of the protein.
About 10% of patients with Parkinson’s disease meeting clinical criteria have a negative result.
The FDA issued a Letter of Support encouraging scientists and drug developers to use alpha-synucin testing in cerebrospinal fluid.
VR Score
87
Informative language
86
Neutral language
62
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semi-formal
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English
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59
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long-living
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6
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