TETRIS Mapes Protein Interactions

This is a news story, published by MSN, that relates primarily to TETRIS news.

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diverse protein interactions

Phys Org

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DNA nanotechnology unravels complex protein interactions to inform cancer diagnostics

Summary

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90% Informative

A team of researchers from NUS Institute for Health Innovation & Technology ( iHealthtech ) has developed a first -of-its-kind technology to map out diverse protein interactions in cells using DNA barcodes.

The technology, dubbed TETRIS , can explicitly identify and quantify multiple interacting partners in large protein assemblies.

By capturing the complex hierarchy of protein interactions within tumor cells, the technology uncovers detailed molecular mechanisms driving disease progression.

NUS researchers plan to expand the application of TETRIS to other types of cancers and neurological diseases.

The team has filed two patents for the technology and hopes to commercialize the innovation.

The technology can be used in a doctor's office, where samples obtained via fine-needle aspiration can be rapidly analyzed to inform treatment decisions.

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