Drug Impact on Gut Microbiome Resilience
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microbiome communitiesScienceDaily
•Better together: Gut microbiome communities' resilience to drugs
81% Informative
EMBL Heidelberg researchers compared the effect of 30 diverse drugs on bacteria when they were grown in isolation versus as part of a complex community.
Bacteria that are sensitive to drugs can become resilient when part of communities, with the help of cross-protection strategies.
Mapping and understanding emergent drug-microbiome interactions within the community context may help scientists design improved therapies with fewer side effects and higher drug efficacy in the future.
In the future, we might be able to use this knowledge to tailor prescriptions to reduce drug side effects.
Peer Bork , Group Leader and Director at EMBL Heidelberg , is also studying how interspecies interactions are shaped by nutrients so that we can create even better models for understanding the interactions between bacteria, drugs, and the human host.
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