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A switch for immune memory and anti-tumor immunity

ScienceDaily
Summary
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78% Informative

A study has identified a metabolic switch in the immune system's T cells that is essential to the generation of memory T cells.

The switch's dysfunction compromises T cell "memory" of previously encountered viruses as well as the induction of anticancer immune responses in mice.

"Our findings suggest that we might be able to engage this switch pharmacologically to improve the efficacy of cancer immunotherapies," says researcher Ping-Chih Ho .

"Targeting PPAR/ signaling may be a promising approach to improve T cell-mediated anti-tumor immunity," says Alessio Bevilacqua .

Ping-Chih Ho is a member of the Lausanne Branch of the Ludwig Institute for Cancer Research .

VR Score

88

Informative language

96

Neutral language

34

Article tone

formal

Language

English

Language complexity

68

Offensive language

not offensive

Hate speech

not hateful

Attention-grabbing headline

not detected

Known propaganda techniques

not detected

Time-value

long-living

External references

no external sources

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