logo
welcome
The Conversation

The Conversation

A common parasite could one day deliver drugs to the brain − how scientists are turning ‘Toxoplasma gondii’ from foe into friend

The Conversation
Summary
Nutrition label

73% Informative

A new study has pioneered the use of a single-celled parasite, Toxoplasma gondii, to inject therapeutic proteins into brain cells.

Microbes as medicine has been on a quest to keep infectious agents out of our bodies since the 19th-century germ theory of disease.

The widespread prevalence of Toxoplasma infections disqualifies many people from using it for treatment.

Engineering benign forms of this parasite could produce the proteins patients need without harming the organ the brain that defines who we are.

In some cases, the benefits of using it as a drug delivery system may outweigh the risks.

VR Score

63

Informative language

56

Neutral language

40

Article tone

informal

Language

English

Language complexity

66

Offensive language

likely offensive

Hate speech

possibly hateful

Attention-grabbing headline

not detected

Known propaganda techniques

not detected

Time-value

long-living

External references

36

https://theconversation.com/our-blood-brain-barrier-stops-bugs-and-toxins-getting-to-our-brain-heres-how-it-works-230965https://theconversation.com/institutions/indiana-university-1368?utm_source=Yahoo&utm_medium=related-link&utm_campaign=byline-link&utm_content=article-235928https://www.mayoclinic.org/diseases-conditions/rett-syndrome/symptoms-causes/syc-20377227https://doi.org/10.1038/s41564-024-01750-6https://www.cdc.gov/vaccines/vpd/vaccines-list.htmlhttps://doi.org/10.1007%2Fs40199-019-00291-2https://doi.org/10.1079/ahr2005100https://curiosity.lib.harvard.edu/contagion/feature/germ-theoryhttps://theconversation.com/profiles/bill-sullivan-703249?utm_source=Yahoo&utm_medium=related-link&utm_campaign=byline-link&utm_content=article-235928http://theconversation.com/us?utm_source=Yahoo&utm_medium=related-link&utm_campaign=related-link-0&utm_content=article-235928https://doi.org/10.1016/S2468-1253(22)00276-Xhttps://doi.org/10.1016/j.neubiorev.2018.11.012https://theconversation.com/toxoplasma-is-a-common-parasite-that-causes-birth-defects-but-the-us-doesnt-screen-for-it-during-pregnancy-232936https://doi.org/10.1371/journal.pmed.1001920https://doi.org/10.1258%2Fjrsm.2012.12k044https://doi.org/10.1155%2F2021%2F6634807https://theconversation.com/alzheimers-disease-is-partly-genetic-studying-the-genes-that-delay-decline-in-some-may-lead-to-treatments-for-all-205914https://wellcomecollection.org/works/cq7sx6ak/images?id=crcz8r3shttps://www.drugs.com/drug-classes.html#Bhttps://theconversation.com/lady-mary-wortley-montagu-the-forgotten-immunisation-pioneer-164256https://doi.org/10.1128/cmr.00005-17https://theconversation.com/biologics-the-pricey-drugs-transforming-medicine-80258https://www.cdc.gov/c-diff/index.htmlhttps://theconversation.com/tenacious-curiosity-in-the-lab-can-lead-to-a-nobel-prize-mrna-research-exemplifies-the-unpredictable-value-of-basic-scientific-research-214770https://theconversation.com/benjamin-franklins-fight-against-a-deadly-virus-colonial-america-was-divided-over-smallpox-inoculation-but-he-championed-science-to-skeptics-161569https://doi.org/10.1038/s41392-021-00487-6https://medlineplus.gov/genetics/gene/mecp2/https://theconversation.com/newly-discovered-genetic-variant-that-causes-parkinsons-disease-clarifies-why-the-condition-develops-and-how-to-halt-it-226435http://theconversation.com/toxoplasma-is-a-common-parasite-that-causes-birth-defects-but-the-us-doesnt-screen-for-it-during-pregnancy-232936?utm_source=Yahoo&utm_medium=related-link&utm_campaign=related-link2&utm_content=article-235928https://www.cdc.gov/toxoplasmosis/about/index.htmlhttps://www.rettsyndrome.org/clinical-trial-news-updates/http://creativecommons.org/licenses/by/4.0/https://medicine.iu.edu/faculty/13502/sullivan-williamhttps://doi.org/10.1111/j.1550-7408.2008.00345.xhttp://theconversation.com/tenacious-curiosity-in-the-lab-can-lead-to-a-nobel-prize-mrna-research-exemplifies-the-unpredictable-value-of-basic-scientific-research-214770?utm_source=Yahoo&utm_medium=related-link&utm_campaign=related-link0&utm_content=article-235928http://theconversation.com/whooping-cough-can-be-deadly-for-young-babies-vaccination-is-our-best-defence-235527?utm_source=Yahoo&utm_medium=related-link&utm_campaign=related-link1&utm_content=article-235928

Affiliate links

no affiliate links