Lab-Inspired Neurons Capture Alzheimer's

This is a St. Louis news story, published by MSN, that relates primarily to Washington University School of Medicine news.

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Alzheimer

Medical Xpress - medical research advances and health news

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With new technique, patient-derived neurons accurately model late-onset Alzheimer's disease

Summary

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90% Informative

Researchers at Washington University School of Medicine in St. Louis have developed a way to capture the effects of aging in the development of Alzheimer's disease.

They devised a method to study aged neurons in the lab without a brain biopsy.

The lab-derived neurons accurately reproduced the hallmarks of this type of dementia, including the amyloid beta buildup and tau protein deposits.

The researchers are planning future studies with spheroids that include multiple types of brain cells.

An application for a U.S. patent related to this work has been filed by Washington University , titled " Three -dimensional direct neural reprogramming to model Alzheimer's disease in human neurons".

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English

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